Watches of Switzerland lifts its outlook as US sales jump 22%
Britain’s biggest Rolex seller now expects revenue growth at the top of its 7–10% range; the CEO still warns of uncertainty before Christmas.
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Tod’s creative director Matteo Tamburini steps down after almost three years
The Italian label says it will sharpen its focus on heritage, craftsmanship and Italian identity; no successor has been named.
Zara owner Inditex backs a World Bank-led fund aiming to raise $400 million to decarbonise fashion suppliers
The D-TAFS fund, launched by the IFC and SIMA, will lend to textile, apparel and footwear factories in emerging markets for renewable energy, new machinery and water treatment.
Opioid overdose is rare in cancer patients, but risk rises with high doses, Ontario study finds
Among 554,316 Ontario adults with newly diagnosed solid tumours, 0.3% had a non-fatal and 0.03% a fatal opioid overdose; recent high-dose prescriptions were linked to about 3.5 times the overdose rate. The observational study shows associations, not causes.
Next-generation KRAS drug divarasib beats older pills in lung cancer, extending survival
In the phase 3 Krascendo 1 trial, now highlighted by Nature Medicine, divarasib extended median overall survival to 17.7 months versus 12.0 months with sotorasib or adagrasib in previously treated KRAS G12C-mutated lung cancer. The trial was open-label and funded by Roche.
CAR-T for hard-to-treat lupus: pooled data on 243 patients show sharp drop in disease activity
A systematic review presented at ACR Convergence 2026 by Hospital for Special Surgery pooled 31 studies of CAR T-cell therapy in 243 people with refractory lupus: average disease activity fell from 13.0 to 2.2 at six months, mostly with mild side effects. The underlying studies are small.
New York opens a state AI testing centre and a registration portal for frontier labs
Governor Kathy Hochul launched the New York Center for AI Responsibility and Research at Binghamton University and opened the RAISE Act portal where large frontier AI developers must register by 1 January 2027.
DeepMind's AI agents mathematically verify Signal's encryption code in four weeks
Google DeepMind says its new AlphaProof Code framework proved key security properties of the compiled code behind the Signal protocol, generating about 6.5 million lines of machine-checked Lean proofs. The work covers specific properties, not the whole Signal app.
Anthropic turns Claude into an office suite with Sheets, Whiteboards and Data
Anthropic added collaborative spreadsheets, whiteboards and data dashboards to Claude, let partner apps such as Adobe and Atlassian run inside it, and said a Claude Meetings note-taker is coming soon.
World stocks rise as CoreWeave revives the AI trade; Nvidia rebounds after losing $430 billion in two days
CoreWeave said it expects to turn profitable on an adjusted basis in the first half of 2028; Nasdaq futures jumped about 2% and Asian tech shares rallied.
US consumer prices rise 0.4% in October, beating forecasts and locking in bets on a December Fed rate hike
Headline CPI rose 0.4% and core CPI 0.3%, both above economists’ forecasts; the BLS published no annual rate because of last year’s shutdown.
Ukrainian drones hit Russia’s Ust-Luga port; Pulkovo airport closes, two killed in Smolensk region
The Leningrad region governor said 150 drones were shot down and three port workers injured; pro-war bloggers reported Russian pilots killed during the air defence effort.